carcinogenesis tests การใช้

Various studies have indicated that Trichothecinol A isolated from " T . roseum " strongly inhibited TPA-induced tumour promotion on mouse skin in carcinogenesis tests and therefore may be valuable for further investigation as cancer preventive agent.
Bruce Ames himself argued against linear dose-response extrapolation from the high dose used in carcinogenesis tests in animal systems to the lower dose of chemicals normally encountered in human exposure, as the results may be false positives due to mitogenic response caused by the artificially high dose of chemicals used in such tests.